TUDCA: Benefits, Dosage, Warnings & Where To Buy
There’s a new functional medicine beast on the block, and most people refer to it as “Tudca”. In this review, we are going to cover TUDCA benefits, and the general effects it can have.
More than that, we will look at the science behind TUDCA use on humans, where it comes from, the correct TUDCA dosage range, and the exact results you can hope to benefit from. Plus, this guide will also cover the different formats of Tudca supplements and which is best, side effects and warnings, and where to find TUDCA for sale.
TUDCA has been linked to insane weight loss. So how much weight can you cut, and how quickly? Read on to find out.
What Exactly Is “TUDCA”?
I’m afraid I have to get technical here but don’t worry it will only last a moment and will help you to understand exactly what this supplement is.
Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA), which is a secondary bile acid. It is made only by intestinal bacteria in a range of species. Humans make it, but various types of bears actually have a far higher concentration than we do.
So it does occur naturally in the human body, along with most other mammals. That’s why it’s been known about, and has been used therapeutically in traditional medicine for hundreds of years, and possibly in Chinese medicine for more than 1000 years.
Traditional benefits of TUDCA include liver detoxification, fever, heat-related issues (spasms & vision), neuroprotective properties, and improved cognitive functioning. That’s why some people confusingly refer to TUDCA as a nootropic (smart drug).
However, a new and crucial benefit appears to be its ability to stimulate significant amounts of weight loss. This has led to it being one of the most up-and-coming underground weight loss supplements in the past year.
So what we have got here is basically bile acid. Made from water, various acids, electrolytes, and other organic molecules, they have a key role in mammals’ bodies of helping with digestion, including the absorption of fat-soluble vitamins.
On top of that, bile helps to get rid of cholesterol, bacteria, other types of waste and is part of what regulates metabolism. So this is complex stuff.
But don’t worry, when you buy a TUDCA supplement, you’re not getting pills, liquid, or powder made from bear bile, or even worse, human bile.
What you’re getting is an artificial construction. In fact, it’s fermented and then goes through a conversion process to create TUDCA. So it’s not created in the body, it is artificially created through industrial techniques.
That’s how we get the modern supplement. I’m not entirely sure how the ancient Chinese got hold of the TUDCA they used medicinally, and to be honest, like you, I’m pretty sure I don’t want to know!
TUDCA Effects & Benefits
Bile salts of various types are released into your intestines as needed through the liver bile duct. Once in your large intestine, they are metabolized into bile salts primarily through interaction with cholesterol.
Bile salts once metabolized become something called UDCA (ursodeoxycholic acid). After circulation, these acids return to the liver, where they are conjugated with taurine to create TUDCA. So primary bile acids are metabolized into UDCA bile salts, and the secondary ones after this reprocessing are called TUDCA.
TUDCA benefits obviously occur naturally as part of the digestive system, with the side benefits of removal of things like cholesterol and increase absorption of vitamins.
However, when used as a consumable supplement, TUDCA benefits increase to cover:
- Digestive support (increased fat digestion)
- Weight loss potential
- Improving baseline insulin sensitivity
- Better eye health
- Body detoxification
- Neuroprotective properties
- Mitochondria & cellular support
- Increased liver health
- Better nutrient absorption
- Increased gut health
- Kidney protection
As you can see, the list of benefits of using this naturally occurring bile acid is quite impressive. Let’s quickly take a look at several of the key benefits in detail.
- Mitochondria & cellular support doesn’t sound impressive until we explain exactly what that means. Mitochondria are found in every cell in the body, and they generate around 90% of the energy produced by the body at the cellular level. Increasing the health and stability of this through using TUDCA can produce more antioxidants, decrease free radicals, cellular mutations, and regulation of apoptosis (programmed cell death).
- TUDCA may help support insulin sensitivity. Studies have found that this supplement can deliver a significant reduction in blood glucose when administered. Animal studies showed up to a 43% reduction in blood sugar levels, which could have a huge impact on diabetes.
- TUDCA supplementation has been proven to generate a dramatically increased level of bile flow. That means better digestion, more complete absorption of key nutrients and a faster and more complete passage out of the body for things like cholesterol and other damaging products.
- Easily crossing the blood-brain barrier, TUDCA has been the focus of several studies around neuroprotective chemical properties. As well as having mitochondrial support, which can lower cell mutations, and increased cell longevity, it’s also been shown to be a “chemical chaperone”, that can help to move proteins to their correct destination in the brain, where poor processing could lead to the building up and causing cognitive decline.
TUDCA Weight Loss
TUDCA has been linked to strong weight loss potential. As “Nature” Magazine wrote:
“As already shown, we observed that TUDCA treatment decreased bodyweight due to a reduction in fat pad deposits, which was associated with improved glucose tolerance and insulin sensitivity”
So TUDCA could offer exciting potential to cut significant amounts of weight easily.
TUDCA Dosage Range & Cycle Length
Overall, TUDCA supplementation can have a range of health benefits, the most notable of which are increased gut health and improved digestion/eradication, as well as the tantalizing prospect of it improving your brain health over time.
But how do you actually take TUDCA?
Because this is a supplement that has never been through full human testing or licensed for use for any purpose, it’s tough to talk about standardized dosing for TUDCA.
Anecdotally, and using the limited human studies out there as a basis, a low dose appears to be around 150 mg. Most supplements that are dosed by capsule appear to be around 1-250 mg, although some can be 500 mg.
Studies in humans have actually also used doses as high as 1500 mg per day. Generally, because of the effect, it has on your body, it may not be advisable to take more than 1500 mg per day.
For me, I would suggest you start at 150 mg per day for a week, then double it to 500 mg per week and see how you feel.
If you intend to use TUDCA to try and derive long-term benefits, such as neuroprotective ones, then I would suggest a daily dose of 3-500 mg is the range you should be looking at.
Forms of TUDCA Supplements
TUDCA is mostly available in pill form. Usually, these are capsules filled with powder rather than solid pills. You can get TUDCA liquid, but my own experience has been with capsules. It might be worth experimenting with both forms to see which works best for you.
Certainly, capsules, it allows them to get into the stomach before they start to be absorbed, which could be more beneficial than liquid.
I guess my advice based on using supplements over the years is to not buy raw TUDCA powder. Although you’ll find it far cheaper than you will capsule, it’s also more difficult to deal with. You have to weigh it, put it into a form you consume it, and deal with the dusty aftertaste.
Side Effects & Warnings Related To using TUDCA
TUDCA supplements are mostly considered safe within normal dosage ranges, and it certainly widely available in most countries.
Stick to the low-end dose, and don’t exceed 1500 mg per day, and you shouldn’t have any problems. At high doses, people have reported stomach pains, nausea, and diarrhea. That’s actually not that unusual with high doses of any supplement or chemical put into the body.
However, sticking to lower doses seems to minimize the chances of digestive upset occurring. Taking 500 mg per day for several months, I never experienced any side effects at all, and still don’t.
Where To Find TUDCA For Sale
TUDCA seems to be a very low-risk way of increasing several beneficial effects in the body and helping to minimize some longer-term problems that can affect people quite seriously.
For me, it’s that link to long-term improved neurological health and increased mitochondrial function that is attractive. Alongside that, you get the short-term benefits of better digestion, better absorption, and a more thorough elimination of waste from the body (especially cholesterol).
TUDCA supplements can be bought quite widely. However, I’d always advocate buying them from specialist online retailers who can show you a track record of batch testing through independent third-party labs to show that what they are selling is pure and effective.
Swiss Chems sell TUDCA capsules at a very reasonable price. That’s where I get them from.
For just $24.95, you can buy 60 capsules, each dosing 150 mg. So each capsule is enough for a low dose, paired up for a medium dose, or taken three times they can deliver what I would call the optimum dose.
On top of that, Swiss Chems have a very wide range of supplements, including peptides of various types, that can have a range of positive benefits in the body, and all are available at a great price. It’s certainly the sort of place you could buy several supplements at once to save quite a lot of money compared to buying them individually.